WebPhospho-RB1-S780 pAb. 770-729-2992. Cart Is Empty. Cart Is Empty. View Cart. Checkout. Comparison List; Sign In WebProduct information "Anti-phospho-RB1, (S780) (Retinoblastoma-associated Protein, pRb, Rb, PP110, P105-Rb)" RB1 likely acts as a regulator of other genes. It forms a complex …
PARP Inhibition Suppresses GR-MYCN-CDK5-RB1-E2F1 Signaling …
WebAug 6, 2007 · The c-MET receptor can be overexpressed, amplified, or mutated in solid tumours including small cell lung cancer (SCLC). In c-MET-overexpressing SCLC cell line NCI-H69, hepatocyte growth factor (HGF) dramatically induced c-MET phosphorylation at phosphoepitopes pY1230/1234/1235 (catalytic tyrosine kinase), pY1003 … WebAug 4, 2024 · Western blot analysis of PARP1 cleavage and RB1, pRB1 S780, and CDK6 expressions in MDAH cells transduced as indicated and treated with vehicle (V) or with CBDCA, as in (B), and then released (R) for 8 and 24 h. Cell cycle distribution of MDAH cells transduced with control or CDK6-specific shRNAs, evaluated by flow cytometry 72 h post … detwiler v zoning hearing board case brief
Downstream signalling and specific inhibition of c-MET/HGF
WebWestern blot analysis of extracts of C6 cells, using Phospho-RB-S780 Rabbit mAb (AP0117) at 1:1000 dilution.C6 cells were treated by 10% FBS at 37℃ for 30 minutes after serum-starvation overnightSecondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in … WebANTI-PHOSPHO-RB(S780) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution; Synonyms: RB1,Retinoblastoma-associated protein,p105-Rb,pRb,pp110; … WebCDDD2-94 inhibits S780-phosphorylated Rb (pRb(S780)) and decreases transcription of Rb1 and E2F-target genes in MDA-MB-453 cells. CDDD2-94 is well tolerated and efficacious in preclinical OC xenograft model, CDDD2-94 provides better safety profile than palbociclib towards the bone marrow. detwillers mcarthur ohio